Article
A paired-sibling analysis of the XbaI polymorphism in the muscle glycogen synthase gene.
Diabetologia - 1 Sept 1999
Orho-Melander M, Almgren P, Kanninen T, Forsblom C, Groop L C
Abstract excerpt
AIMS/HYPOTHESIS: We have previously shown an association between a XbaI polymorphism in the muscle glycogen synthase gene (GYS1) and both Type II (non-insulin-dependent) diabetes mellitus and hypertension. Association studies are, however, hampered by the selection of the control group. To circumvent these problems we addressed the same question using a novel genotype discordant paired-sibling approach. METHODS:...
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