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Allele specific C-bulge probes with one unique fluorescent molecule discriminate the single nucleotide polymorphism in DNA.

Chemistry (Weinheim an der Bergstrasse, Germany) - 1 Jan 2007

Takei Fumie, Suda Hitoshi, Hagihara Masaki, Zhang Jinhua, Kobori Akio, Nakatani Kazuhiko

Abstract excerpt

A combination of an allele specific C-bulge probe and the fluorescent molecule N,N'-bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine (DANP) that binds specifically to the C-bulge provides a method for single nucleotide polymorphism (SNP) typing with only one fluorescent molecule without covalent modification of the DNA probe. The allele specific C-bulge probe contains one additional cytosine and produces a...

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PMID: 17352435
DOI: 10.1002/chem.200601496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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