Article
Selection promotes organ compartmentalization in HIV-1: evidence from gag and pol genes.
Evolution; international journal of organic evolution - 1 Feb 2007
Bordería Antonio V, Codoñer Francisco M, Sanjuán Rafael
Abstract excerpt
The existence of organ-specific human immunodeficiency virus type 1 (HIV-1) populations within infected hosts has been long lasting studied. Previous work established that population subdivision by organs occurs at the envelope env gene, but less is known about other genomic regions. Here, we used a population genetics approach to detect organ compartmentalization in proviral sequences of HIV-1 gag and pol genes....
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