Article
At least five polymorphic mutants account for the prevalence of glucose-6-phosphate dehydrogenase deficiency in Algeria.
Human genetics - 1 Nov 1994
Nafa K, Reghis A, Osmani N, Baghli L, Aït-Abbes H, Benabadji M, Kaplan J C, Vulliamy T, Luzzatto L
Abstract excerpt
The electrophoretic mobility and level of enzyme activity of glucose-6-phosphate dehydrogenase (G6PD) was established in 100 unrelated Algerian males with G6PD deficiency. DNA from these subjects was analysed for the presence of certain known G6PD mutations by the appropriate restriction enzyme d...
Topics
- Algeria
- Base Sequence
- DNA Mutational Analysis
- Exons
- Favism
- Genetic Heterogeneity
- Genetic Variation
- Glucosephosphate Dehydrogenase
- Glucosephosphate Dehydrogenase Deficiency
- Haplotypes
- Humans
- Male
- Molecular Sequence Data
- Point Mutation
- Polymorphism, Restriction Fragment Length