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Article

Cloning and Expression of IDDM-Specific Human Autoantigens

1 Feb 1992

Abstract excerpt

A DNA cloning approach was taken to identify islet cell protein antigens that are recognized specifically by insulin-dependent diabetes mellitus (IDDM) sera. A human islet cDNA library was generated and screened with diabetic sera. In this article, identification of two clones is described. Proteins expressed by these lambda phages appeared to react specifically with newly diagnosed diabetic sera. Islet cell...

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Identifiers

PMID: 1733807
DOI: 10.2337/diab.41.2.183

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