Article
Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group.
Diabetes/metabolism research and reviews - 1 Nov 2009
Malhotra Alka, Igo Robert P, Thameem Farook, Kao W H Linda, Abboud Hanna E, Adler Sharon G, Arar Nedal H, Bowden Donald W, Duggirala Ravindranath, Freedman Barry I, Goddard Katrina A B, Ipp Eli, Iyengar Sudha K, Kimmel Paul L, Knowler William C, Kohn Orly, Leehey David, Meoni Lucy A, Nelson Robert G, Nicholas Susanne B, Parekh Rulan S, Rich Stephen S, Chen Yii-Der I, Saad Mohammed F, Scavini Marina, Schelling Jeffrey R, Sedor John R, Shah Vallabh O, Taylor Kent D, Thornley-Brown Denyse, Zager Philip G, Horvath Amanda, Hanson Robert L
Abstract excerpt
BACKGROUND: Previous studies have shown that in addition to environmental influences, type 2 diabetes mellitus (T2DM) has a strong genetic component. The goal of the current study is to identify regions of linkage for T2DM in ethnically diverse populations. METHODS: Phenotypic and genotypic data were obtained from African American (AA; total number of individuals [N] = 1004), American Indian (AI; N = 883),...
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