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Article

Uncoupling of hormone-dependence from chaperone-dependence in the L701H mutation of the androgen receptor.

Molecular and cellular endocrinology - 30 Mar 2007

Robzyk Kenneth, Oen Handy, Buchanan Grant, Butler Lisa M, Tilley Wayne D, Mandal Atin K, Rosen Neal, Caplan Avrom J

Abstract excerpt

The mechanisms underlying androgen receptor (AR)-mediated progression of prostate cancer following androgen ablation have yet to be fully determined. On this basis we screened naturally occurring mutants of human AR for hormone-independent activity using a yeast model system. An initial screen of...

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Identifiers

PMID: 17336451
DOI: 10.1016/j.mce.2007.01.016
PMCID: PMC1904484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17336451-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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