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Article

Pan‐myocardial expression of Cre recombinase throughout mouse development

1 Mar 2007

Abstract excerpt

Mouse-lines expressing Cre recombinase in a tissue-specific manner are a powerful tool in developmental biology. Here, we report that a 3 kb fragment of the Xenopus laevis myosin light-chain 2 (XMLC2) promoter drives Cre recombinase expression in a cardiac-restricted fashion in the mouse embryo. We have isolated two XMLC2-Cre lines that express recombinase exclusively within cardiomyocytes, from the onset of...

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PMID: 17334998
DOI: 10.1002/dvg.20275

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