Article
IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations.
Stroke - 1 Apr 2007
Worrall Bradford B, Brott Thomas G, Brown Robert D, Brown W Mark, Rich Stephen S, Arepalli Sampath, Wavrant-De Vrièze Fabienne, Duckworth Jaime, Singleton Andrew B, Hardy John, Meschia James F
Abstract excerpt
BACKGROUND AND PURPOSE: Genetic factors influence risk for ischemic stroke and likely do so at multiple steps in the pathogenic process. Variants in genes related to inflammation contribute to risk of stroke. The purpose of this study was to confirm our earlier finding of an association between allele 2 of a variable number tandem repeat of the IL-1 receptor antagonist gene (IL1RN) and cerebrovascular disease....
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