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Article

Noninactivation of a portion of Xq28 in a balanced X-autosome translocation.

American journal of medical genetics - 15 Jan 1992

Du Sart D, Kalitsis P, Schmidt M

Abstract excerpt

We present a balanced translocation (X;9) (q28;q21) in which the normal X chromosome is preferentially active. The derivative X chromosome is inactive in 93% of fibroblasts, but the X portion translocated onto chromosome 9 is not inactivated, as apparent from DNA methylation and chromosome replication patterns. Consequently, the patient is functionally disomic for the part of Xq28 distal to the locus LICAM.

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Source

Identifiers

PMID: 1733163
DOI: 10.1002/ajmg.1320420204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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