Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOD2 polymorphisms: unmasking the effect of polymorphism on splicing.

BMC medical genetics - 1 Mar 2007

Shao Jing, Chen Lishan, Marrs Brian, Lee Lin, Huang Hai, Manton Kenneth G, Martin George M, Oshima Junko

Abstract excerpt

BACKGROUND: The SOD2 gene encodes an antioxidant enzyme, mitochondrial superoxide dismutase. SOD2 polymorphisms are of interest because of their potential roles in the modulation of free radical-mediated macromolecular damage during aging. RESULTS: We identified a new splice variant of SOD2 in human lymphoblastoid cell lines (LCLs). The alternatively spliced product was originally detected by exon trapping of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Alternative Splicing
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Transformed

Share to Gene Frequency

Share to Introns

Share to Lymphocytes

Share to Superoxide Dismutase

Source

Open in PubMed Open full text

Identifiers

PMID: 17331249
DOI: 10.1186/1471-2350-8-7
PMCID: PMC1819367

Genes

SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOD2 polymorphisms: unmasking the effect of polymorphism on splicing.PMID 17331249Read ↗

Functional analysis of BRCA1 and BRCA2 splicing variants using a minigene assay.Semantic proximity Read ↗

Effect of BRCA2 sequence variants predicted to disrupt exonic splice enhancers on BRCA2 transcripts.Semantic proximity Read ↗

BRCA2 deep intronic mutation causing activation of a cryptic exon: opening toward a new preventive therapeutic strategy.Semantic proximity Read ↗

Screening BRCA1 and BRCA2 unclassified variants for splicing mutations using reverse transcription PCR on patient RNA and an ex vivo assay based on a splicing reporter minigene.Semantic proximity Read ↗

Direct detection and automated sequencing of individual alleles after electrophoretic strand separation: identification of a common nonsense mutation in exon 9 of the human lipoprotein lipase gene.Semantic proximity Read ↗

Manganese superoxide dismutase V16A single-nucleotide polymorphism in the mitochondrial targeting sequence is associated with reduced enzymatic activity in cryopreserved human hepatocytes.Semantic proximity Read ↗

Ethnic variation in the mitochondrial targeting sequence polymorphism of MnSOD.Semantic proximity Read ↗

A novel Real Time PCR strategy to detect SOD3 SNP using LNA probes.Semantic proximity Read ↗

Identification of a novel single nucleotide polymorphism (SNP) in the human organic cation transporter-like 2-antisense (ORCTL2S) gene.Semantic proximity Read ↗

A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol.Semantic proximity Read ↗

Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics.Semantic proximity Read ↗

Association of a new intronic polymorphism of the SOD2 gene (G1677T) with cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.