Article
Huntington's disease confirmed by genetic testing in five African families.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 1998
Silber E, Kromberg J, Temlett J A, Krause A, Saffer D
Abstract excerpt
Huntington's disease is an autosomal-dominant inherited progressive neurodegenerative disease associated with an expanded trinucleotide repeat (CAG) sequence on the short arm of chromosome 4. The disease is considered rare in Africans. We report five black South African families of different ethn...
Topics
- Black People
- Chromosome Aberrations
- Chromosome Disorders
- Female
- Genes, Dominant
- Genetic Testing
- Humans
- Huntington Disease
- Male
- Pedigree
- Phenotype
- South Africa
- Trinucleotide Repeats
- White People