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Article

Huntington's disease confirmed by genetic testing in five African families.

Movement disorders : official journal of the Movement Disorder Society - 1 Jul 1998

Silber E, Kromberg J, Temlett J A, Krause A, Saffer D

Abstract excerpt

Huntington's disease is an autosomal-dominant inherited progressive neurodegenerative disease associated with an expanded trinucleotide repeat (CAG) sequence on the short arm of chromosome 4. The disease is considered rare in Africans. We report five black South African families of different ethnic origin with proven expansions typical of Huntington's disease and discuss the possible origins of the disease in Africa.

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Identifiers

PMID: 9686782
DOI: 10.1002/mds.870130420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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