Article
Phenotyping of chondrocytes in vivo and in vitro using cDNA array technology.
Clinical orthopaedics and related research - 1 Jul 2007
Zien Alexander, Gebhard Pia Margarethe, Fundel Katrin, Aigner Thomas
Abstract excerpt
The cDNA array technology is a powerful tool to analyze a high number of genes in parallel. We investigated whether large-scale gene expression analysis allows clustering and identification of cellular phenotypes of chondrocytes in different in vivo and in vitro conditions. In 100% of cases, clustering analysis distinguished between in vivo and in vitro samples, suggesting fundamental differences in chondrocytes...
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