Article
Identification of genotypes of plasmid-encoded AmpC beta-lactamases from clinical isolates and characterization of mutations in their promoter and attenuator regions.
Gene expression - 1 Jan 2012
Li Gui-Ling, Duo Li-Bo, Luan Ying, Wang Cheng-Ying, Wang Wei-Ping, Zhang He-Guang, Sun Qi, Qi Gui-Yun
Abstract excerpt
We investigated the occurrence of AmpC beta-lactamases among Escherichia coli and Klebsiella pneumoniae isolates and determined the genotype of plasmid-mediated AmpC beta-lactamases at a medical center. The AmpC beta-lactamase promoter and attenuator were amplified from chromosomal DNA of high AmpC-producing E. coli isolates and sequenced. Antibiotic screening and 3D extract tests showed the presence of AmpC...
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