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Article

Association between cytochrome P450 (CYP) 2C19 polymorphisms and harm avoidance in Japanese.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2007

Yasui-Furukori Norio, Kaneda Ayako, Iwashima Kumiko, Saito Manabu, Nakagami Taku, Tsuchimine Shoko, Kaneko Sunao

Abstract excerpt

Polymorphic enzyme cytochrome P450 (CYP) 2C19 is expressed not only in the liver but also in the brain and mediates the biotransformation of 5-hydroxytriptamine (5-HT). We investigated possible association between genetic polymorphism of CYP2C19 and individual personality traits, possibly influenced by neurotransmitters. Mentally and physically healthy Japanese subjects were enrolled in this study (n = 352)....

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PMID: 17357148
DOI: 10.1002/ajmg.b.30430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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