Article
The interaction of host genetic factors and Helicobacter pylori infection.
Inflammopharmacology - 1 Feb 2007
Ando T, Goto Y, Ishiguro K, Maeda O, Watanabe O, Ohmiya N, Niwa Y, Hamajima N, El-Omar E, Goto H
Abstract excerpt
Helicobacter pylori plays an important role in the development of atrophic gastritis that represents the most recognized pathway in multistep gastric carcinogenesis. Recent studies suggest that a combination of host genetic factors, bacterial virulence factors, and environmental and lifestyle factors determine the severity of gastric damage and the eventual clinical outcome of Helicobacter pylori infection. As to...
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