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Pathogenesis of Helicobacter pylori Infection

16 Aug 2006

Abstract excerpt

Much interest has been shown in the relationship between Helicobacter pylori infection and gastric carcinogenesis. It is becoming clearer that H. pylori strains carrying a functional cag pathogenicity island (cagPAI), which encodes the type IV secretion system (TFSS) and its effector CagA, play an important role in the development of gastric carcinoma. Furthermore, genetic polymorphism present in the cagA gene...

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PMID: 16925606
DOI: 10.1111/j.1478-405x.2006.00424.x

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