Article
Association of HLA-DQA1*03011-DQB1*0301 haplotype with the development of respiratory scleroma.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Mar 2007
Sánchez-Marín Luis Alberto, Bross-Soriano Daniel, Arrieta José, Kawa-Karasik Simón, Martínez-Vilchis Víctor, Jiménez-Lucio Rocío, Olivo-Díaz Angélica
Abstract excerpt
OBJECTIVE: Respiratory scleroma (RS) is a progressive, chronic, granulomatous disease caused by Klebsiella rhinoscleromatis. There is only one report of RS association with HLA-DQ3. In this study, molecular association of HLA class II and RS was determined. STUDY DESIGN AND SETTING: Nine RS patients and 163 healthy controls were compared. DQA1, DQB1, and DRB1 loci were typed. RESULTS: Statistical analysis...
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