Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The post-translational phenotype of collagen synthesized by SAOS-2 osteosarcoma cells.

Bone - 1 May 2007

Fernandes Russell J, Harkey Michael A, Weis Maryann, Askew Jennifer W, Eyre David R

Abstract excerpt

The human osteosarcoma-derived cell line, SAOS-2, exhibits many of the phenotypic characteristics of osteoblasts including the deposition of types I and V collagens in an extracellular matrix. Lesser amounts of collagen XI chains were also detected. The cell layer collagen contains hydroxylysyl p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Collagen
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Osteosarcoma

Share to Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 17320498
DOI: 10.1016/j.bone.2007.01.011
PMCID: PMC1909750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17320498-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The post-translational phenotype of collagen synthesized by SAOS-2 osteosarcoma cells.PMID 17320498Read ↗

Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomesSemantic proximity Read ↗

Role of Glycosyltransferase 25 Domain 1 in Type I Collagen Glycosylation and Molecular Phenotypes.Semantic proximity Read ↗

Decrease of lysyl hydroxylase 2 activity causes abnormal collagen molecular phenotypes, defective mineralization and compromised mechanical properties of bone.Semantic proximity Read ↗

Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17.Semantic proximity Read ↗

Hydroxylation of collagen type I: evidence that both lysyl and prolyl residues are overhydroxylated in osteogenesis imperfecta.Semantic proximity Read ↗

The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro.Semantic proximity Read ↗

Re-evaluation of lysyl hydroxylation in the collagen triple helix: lysyl hydroxylase 1 and prolyl 3-hydroxylase 3 have site-differential and collagen type-dependent roles in lysine hydroxylationSemantic proximity Read ↗

Type I collagen differences in farmed Chinook salmon (Oncorhynchus tshawytscha) in New ZealandSemantic proximity Read ↗

The Role of the α3(VI) Chain in Collagen VI AssemblySemantic proximity Read ↗

Matrix deposition by a calcifying human osteogenic sarcoma cell line (SAOS-2).Semantic proximity Read ↗

Inhibition of lysyl oxidase activity can delay phenotypic modulation of chondrocytes in two-dimensional culture.Semantic proximity Read ↗

Skeletal alkaline phosphatase specific activity is an index of the osteoblastic phenotype in subpopulations of the human osteosarcoma cell line SaOS-2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.