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Article

An analysis of genetic diversity and inbreeding in Wuchereria bancrofti: implications for the spread and detection of drug resistance.

PLoS neglected tropical diseases - 2 Apr 2008

Churcher Thomas S, Schwab Anne E, Prichard Roger K, Basáñez María-Gloria

Abstract excerpt

Estimates of genetic diversity in helminth infections of humans often have to rely on genotyping (immature) parasite transmission stages instead of adult worms. Here we analyse the results of one such study investigating a single polymorphic locus (a change at position 200 of the beta-tubulin gene) in microfilariae of the lymphatic filarial parasite Wuchereria bancrofti. The presence of this genetic change has...

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Identifiers

PMID: 18382607
DOI: 10.1371/journal.pntd.0000211
PMCID: PMC2275205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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