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Article

Influence of anti-filarial chemotherapy strategies on the genetic structure of Wuchereria bancrofti populations.

Memorias do Instituto Oswaldo Cruz - 1 Mar 2011

Ramasamy Dhamodharan, Laxmanappa Hoti Sugeerappa, Sharma Rohit, Das Manoj Kumar

Abstract excerpt

Lymphatic filarial (LF) parasites have been under anti-filarial drug pressure for more than half a century. Currently, annual mass drug administration (MDA) of diethylcarbamazine (DEC) or ivermectin in combination with albendazole (ALB) have been used globally to eliminate LF. Long-term chemotherapies exert significant pressure on the genetic structure of parasitic populations. We investigated the genetic...

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Identifiers

PMID: 21537687
DOI: 10.1590/s0074-02762011000200020

Genes

ALB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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