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Article

Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis.

American journal of medical genetics. Part A - 15 Mar 2007

Vieira Alexandre R, Modesto Adriana, Meira Raquel, Barbosa Anna Renata Schneider, Lidral Andrew C, Murray Jeffrey C

Abstract excerpt

Phenotypic characteristics expressed in syndromes give clues to the factors involved in the cause of isolated forms of the same defects. We investigated two genes responsible for craniofacial syndromes, FGFR1 and IRF6, in a collection of families with isolated tooth agenesis. Cheek swab samples were obtained for DNA analysis from 116 case/parent trios. Probands had at least one developmentally missing tooth,...

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Source

Open in PubMed Open full text

Identifiers

PMID: 17318851
DOI: 10.1002/ajmg.a.31620
PMCID: PMC2570343

Genes

FGFR1
MSX1
TGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis.PMID 17318851Read ↗

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