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Article

A combined targeted mutation analysis of IRF6 gene would be useful in the first screening of oral facial clefts.

BMC medical genetics - 20 Mar 2013

Wu-Chou Yah-Huei, Lo Lun-Jou, Chen Kuo-Ting Philip, Chang Chun-Shin Frank, Chen Yu-Ray

Abstract excerpt

BACKGROUND: Interferon Regulatory Factor 6 (IRF6) is a member of the IRF family of transcription factors. It has been suggested to be an important contributor to orofacial development since mutations of the IRF6 gene has been found in Van der Woude (VWS) and popliteal pterygium syndromes (PPS), two disorders that can present with isolated cleft lip and palate. The association between IRF6 gene and cleft lip and...

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Identifiers

PMID: 23510002
DOI: 10.1186/1471-2350-14-37
PMCID: PMC3606492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A combined targeted mutation analysis of IRF6 gene would be useful in the first screening of oral facial clefts.PMID 23510002Read ↗

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