Article
Polymorphism of the porcine leptin gene promoter and analysis of its association with gene expression and fatness traits.
Biochemical genetics - 1 Apr 2007
Stachowiak M, Mackowski M, Madeja Z, Szydlowski M, Buszka A, Kaczmarek P, Rubis B, Mackowiak P, Nowak K W, Switonski M
Abstract excerpt
We describe for the first time a 245 bp fragment of the porcine leptin gene promoter in the proximity of the transcription start site. Altogether, 720 pigs were screened with the PCR-SSCP technique for polymorphism in this region. Four SNPs, segregating as two haplotypes, have been identified, one of them (C113G) in the putative consensus site for the AP-2 transcription factor. This polymorphism was evenly...
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