Article
Missense mutations in exon 4 of the porcine LEPR gene encoding extracellular domain and their association with fatness traits.
Animal genetics - 1 Apr 2005
Mackowski M, Szymoniak K, Szydlowski M, Kamyczek M, Eckert R, Rozycki M, Switonski M
Abstract excerpt
Three non-synonymous single nucleotide polymorphisms (T221C, T232A and C233T) were detected in exon 4 of the porcine leptin receptor (LEPR) gene. The T232A substitution could be identified as a (Tsp509I) restriction fragment length polymorphism. The frequency of genotype TT varied in six genetic groups from 0.62 (Duroc) to 0.99 (Polish Large White). Sequencing of exon 4, performed for 30 animals, revealed that...
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