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Article

RET proto-oncogene in Sardinia: V804M is the most frequent mutation and may be associated with FMTC/MEN-2A phenotype.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2007

Pinna Giovanni, Orgiana Giuseppina, Riola Alessia, Ghiani Mariangela, Lai Maria Letizia, Carcassi Carlo, Mariotti Stefano

Abstract excerpt

OBJECTIVE: Genetic screening of RET proto-oncogene is a powerful tool for the early identification of familial cases of medullary thyroid carcinoma (MTC), comprising isolated familial thyroid medullary carcinoma (FMTC) and multiple endocrine neoplasia syndromes 2A (MEN-2A) and 2B (MEN-2B). We rep...

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Source

Identifiers

PMID: 17316110
DOI: 10.1089/thy.2006.0198

Genes

RET

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17316110-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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