Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes.

doi:10.1530/EJE-10-0333

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes.

European journal of endocrinology - 1 Aug 2010

Romei Cristina, Mariotti Stefano, Fugazzola Laura, Taccaliti Augusto, Pacini Furio, Opocher Giuseppe, Mian Caterina, Castellano Maurizio, degli Uberti Ettore, Ceccherini Isabella, Cremonini Nadia, Seregni Ettore, Orlandi Fabio, Ferolla Piero, Puxeddu Efisio, Giorgino Francesco, Colao Annamaria, Loli Paola, Bondi Fabio, Cosci Barbara, Bottici Valeria, Cappai Antonello, Pinna Giovanni, Persani Luca, Verga Uberta, Uberta Verga, Boscaro Marco, Castagna Maria Grazia, Cappelli Carlo, Zatelli Maria Chiara, Faggiano Antongiulio, Francia Giuseppe, Brandi Maria Luisa, Falchetti Alberto, Pinchera Aldo, Elisei Rossella

Abstract excerpt

OBJECTIVE: Multiple endocrine neoplasia type 2 (MEN 2) is a genetic disease characterized by medullary thyroid carcinoma (MTC) associated (MEN 2A and 2B) or not familial MTC (FMTC) with other endocrine neoplasia due to germline RET gene mutations. The prevalence of these rare genetic diseases and their corresponding RET mutations are unknown due to the small size of the study population. METHODS: We collected...

Topics

Chi-Square Distribution
Female
Genetic Association Studies
Genetic Testing
Genotype
Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Italy

Male

Multiple Endocrine Neoplasia Type 2a

Multiple Endocrine Neoplasia Type 2b

Pedigree

Phenotype

Proto-Oncogene Proteins c-ret

Source

Open in PubMed

Identifiers

PMID: 20516206
DOI: 10.1530/EJE-10-0333

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes.PMID 20516206Read ↗

Multiple endocrine neoplasia type 2: 2007 update.Semantic proximity Read ↗

Multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Genotype and phenotype landscape of MEN2 in 554 medullary thyroid cancer patients: the BrasMEN studySemantic proximity Read ↗

Genetic and Clinical Features of Multiple Endocrine Neoplasia Types 1 and 2Semantic proximity Read ↗

Genotype-phenotype relationship in multiple endocrine neoplasia type 2. Implications for clinical management.Semantic proximity Read ↗

RET Proto-Oncogene Variants in Patients with Medullary Thyroid Carcinoma from the Mediterranean Basin: A Brief ReportSemantic proximity Read ↗

Multiple endocrine neoplasia type 2.Semantic proximity Read ↗

[Multiple endocrine neoplasia type 2].Semantic proximity Read ↗

Genotype/phenotype correlations in multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Multiple endocrine neoplasia: types 1 and 2.Semantic proximity Read ↗

[Multiple endocrine neoplasia type 2].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.