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Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients

21 Feb 2007

Abstract excerpt

BRAFV600E is the most represented somatic point mutation in cutaneous melanoma, thus providing a unique molecular marker for this disease. The development of efficient methods for its detection in free circulating DNA of patients may lead to the improvement of diagnostic and prognostic tools. With this aim, we evaluated whether BRAFV600E represents a detectable marker in the plasma/serum from melanoma patients in...

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PMID: 17315191
DOI: 10.1002/ijc.22598

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