Article
Association between polymorphisms of DNA repair gene XRCC1 and DNA damage in asbestos-exposed workers.
Biomedical and environmental sciences : BES - 1 Jun 2006
Zhao Xiao-Hong, Jia Guang, Liu Yong-Quan, Liu Shao-Wei, Yan Lei, Jin Yu, Liu Nian
Abstract excerpt
OBJECTIVE: To compare the asbestos-induced DNA damage and repair capacities of DNA damage between 104 asbestos-exposed workers and 101 control workers in Qingdao City of China and to investigate the possible association between polymorphisms in codon 399 of XRCC1 and susceptibility to asbestosis. METHODS: DNA damage levels in peripheral blood lymphocytes were determined by comet assay, and XRCC1 genetic...
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