Distribution and persistence of probiotic <i>Streptococcus salivarius</i> K12 in the human oral cavity as determined by real‐time quantitative polymerase chain reaction

Abstract excerpt

The bacteriocin producer Streptococcus salivarius K12 is used as a probiotic targeting the oral cavity, so our study aimed to assess whether its dispersal and persistence could be monitored using real-time quantitative polymerase chain reaction. To this end, we designed polymerase chain reaction primers and a hybridization probe specifically targeting salA, which encodes for the prepropeptide of salivaricin A....

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