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Article

Screening the human serum proteome for genotype-phenotype associations: an analysis of the IL6 -174G>C polymorphism.

Proteomics - 1 Feb 2007

Hegedus Christine M, Skibola Christine F, Bracci Paige, Holly Elizabeth A, Smith Martyn T

Abstract excerpt

Interleukin (IL)-6 is a circulatory, pleiotropic cytokine with multiple roles in the immune system. Both IL-6 and the IL6 -174G>C promoter polymorphism have been linked to various diseases associated with inflammation. However, the mechanism by which the polymorphism influences disease risk is unclear. We postulated that serum proteome analysis of individuals with different IL6 -174G>C genotypes would provide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17309100
DOI: 10.1002/pmic.200600366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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