Article
Crohn's disease and polymorphism of heat shock protein gene HSP70-2 in the Tunisian population.
European journal of gastroenterology & hepatology - 1 Mar 2007
Zouiten-Mekki Lilia, Karoui Sami, Kharrat Maher, Fekih Monia, Matri Samira, Boubaker Jalel, Filali Azza, Chaabouni Habiba
Abstract excerpt
BACKGROUND AND AIMS: Crohn's disease is a multifactorial disorder with a pivotal role of the genetic component. HSP70-2 gene, located in IBD3 region, has a PstI polymorphic site associated recently with Crohn's disease especially with a perforating form. In this study, we sought to determine whether this polymorphism was associated with Crohn's disease in the Tunisian population and its correlation with clinical...
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