Article
Beta3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects.
Genetics and molecular research : GMR - 1 Jan 2010
Genelhu V A, Francischetti E A, Duarte S F P, Celoria B M J, Oliveira R C, Cabello P H, Pimentel M M G
Abstract excerpt
We determined whether ADRbeta3 polymorphism is associated with obesity-related traits in 140 obese patients. Molecular analysis was performed by PCR and RFLP. Individuals carrying the Arg64 allele had a lower waist-to-hip ratio, higher adiponectin and high-density lipoprotein cholesterol levels, and a tendency towards lower blood pressure. In contrast, Trp64/Trp64 carriers were at greater risk for dysmetabolic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
