Article
Analyses of cytochrome b mutations in Plasmodium falciparum isolates in Thai-Myanmar border.
Travel medicine and infectious disease - 1 Mar 2007
Naoshima-Ishibashi Yasuko, Iwagami Moritoshi, Kawazu Shin-Ichiro, Looareesuwan Sornchai, Kano Shigeyuki
Abstract excerpt
BACKGROUND: The combination of atovaquone and proguanil (Malarone) has been established as a drug of choice to prevent and treat multi-drug resistant Plasmodium (P.) falciparum malaria in travelers. However, several cases of resistance against Malarone have been reported in some parts of Africa, and many of the cases are believed to be associated with mutations at the codon 268 of cytochrome b gene in...
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