Article
Phenotypic expression of human hepatoma cells in culture.
Journal of cellular biochemistry - 1 Apr 2007
Cutroneo Kenneth R, White Sheryl L, Buttolph Thomas R, Allison Gretchen, Ehrlich H Paul
Abstract excerpt
Hepatomas thrive in a hypoxic environment resulting in the induction of a cluster of hypoxia related genes. The protein phenotypic expression include hypoxia inducible factor-alpha, prolyl-4-hydroxylase, vascular endothelear growth factor and erythropoietin. The present study was undertaken to determine if human hepatoma cells when cultured for 72 h in the presence of serum under normoxia would maintain their...
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