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Article

Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks.

Journal of medical entomology - 1 Jan 2007

Nosbisch Leanna K, de Silva Aravinda M

Abstract excerpt

VlsE is a surface exposed lipoprotein of the Lyme disease spirochete, Borrelia burgdorferi. Spirochetes are able to generate many antigenic variants of VlsE by DNA recombination at the vlsE locus. Novel VlsE antigenic variants are readily observed in mice infected with B. burgdorferi. We followed a clonal population of spirochetes through a tick transmission cycle and report that unlike in vertebrates, the vlsE...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17294937
DOI: 10.1603/0022-2585(2007)44[168:lodvab]2.0.co;2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detailed Analysis of Sequence Changes Occurring during vlsE Antigenic Variation in the Mouse Model of Borrelia burgdorferi InfectionSemantic proximity Read ↗

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