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Article

Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin.

Apoptosis : an international journal on programmed cell death - 1 Jul 2007

Nachmias Boaz, Lazar Itay, Elmalech Meital, Abed-El-Rahaman Ihab, Asshab Yaqoub, Mandelboim Ofer, Perlman Riki, Ben-Yehuda Dina

Abstract excerpt

Livin is a member of the Inhibitor of Apoptosis Protein family which inhibits apoptosis induced by a variety of stimuli. We previously identified Livin and demonstrated that following apoptotic stimuli, Livin is cleaved by effector caspases to produce a truncated form with paradoxical pro-apoptotic activity. In the present study, we reveal that while full-length Livin shows diffuse cytoplasmic localization,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17294084
DOI: 10.1007/s10495-006-0049-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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