Article
Functional analysis of the genetic variability in the F7 gene promoter.
Atherosclerosis - 1 Dec 2007
Sabater-Lleal Maria, Chillón Miguel, Howard Tom E, Gil Estel, Almasy Laura, Blangero John, Fontcuberta Jordi, Soria José Manuel
Abstract excerpt
The FVII level is considered a risk factor for cardiovascular disease. Some of the polymorphic differences in the promoter of the F7 gene have been associated with variations in FVII levels. However, linkage disequilibrium among those polymorphisms has made it difficult to pinpoint the true functional variants, so contradictory results have often appeared among various studies. We provide new findings of the...
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