Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells

Abstract excerpt

Lymphatic and blood vascular endothelial cells (ECs) share several molecular and developmental features. However, these two cell types possess distinct phenotypic signatures, reflecting their different biological functions. Despite significant advances in elucidating how the specification of lymphatic and blood vascular ECs is regulated at the transcriptional level during development, the key molecular mechanisms...

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