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Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast

8 Feb 2007

Abstract excerpt

OBJECTIVE: To test the hypothesis that free fetal DNA (ffDNA) circulating in maternal plasma originates mainly from the placenta we studied ffDNA levels in anembryonic pregnancies. METHODS: Maternal blood samples were collected from 15 normal first-trimester pregnancies in which fetal sex was subsequently determined and nine patients with a diagnosis of anembryonic gestation (AG). The Y chromosome DYS14 gene was...

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PMID: 17286310
DOI: 10.1002/pd.1700

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