Article
Genetic diversity of the IL-4, IL-4 receptor and IL-13 loci in mestizos in the general population and in patients with asthma from three subpopulations in Mexico.
International journal of immunogenetics - 1 Feb 2007
López K I M, Martínez S E F, Moguel M C M, Romero L T, Figueroa C S, Pacheco G V, Ibarra B, Corona J S
Abstract excerpt
Asthma is an inflammatory airway disease characterized by increased serum IgE levels, mucus hypersecretion and infiltration of inflammatory cells, and is a multifactorial disease that exhibits genetic heterogeneity. Polymorphisms in the interleukin-4 (C-590T), interleukin-4 receptor (ile50val and gln576arg), and interleukin-13 (arg130gln) genes have been described as susceptibility alleles for asthma. This study...
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