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Article

A new molecular genetic diagnosis of the Btk(xid) mice.

Experimental animals - 1 Jan 2007

Takagi Yumie, Masui Norio, Yasuda Mami, Ono Shiro

Abstract excerpt

A new method of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was developed for genetic typing of a point mutation of the Bruton's tyrosine kinase (Btk) gene in CBA/N mice bearing an X-linked recessive immunodeficiency (xid). Since restriction site useful for RFLP analysis does not exist in the spontaneous mutant Btk(xid) locus, an artificial restriction site was...

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Share to Agammaglobulinaemia Tyrosine Kinase
Share to Mice, Inbred CBA
Share to Molecular Diagnostic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 17283893
DOI: 10.1538/expanim.56.63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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