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Article

Acellular pertussis vaccines and the role of pertactin and fimbriae

1 Feb 2007

Abstract excerpt

The introduction of acellular pertussis (Pa) vaccines in countries with a low uptake of whole-cell pertussis (Pw) vaccines has led to a dramatic reduction in pertussis disease. Diphtheria-tetanus-acellular pertussis (DTPa) vaccines have also ensured continued high level disease protection in these countries following the shift from Pw- to Pa-containing vaccines, and allowed pertussis booster programs to be...

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PMID: 17280478
DOI: 10.1586/14760584.6.1.47

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