Article
Sortase-Catalyzed Assembly of Distinct Heteromeric Fimbriae in Actinomyces naeslundii
4 Feb 2007
Abstract excerpt
Two types of adhesive fimbriae are expressed by Actinomyces; however, the architecture and the mechanism of assembly of these structures remain poorly understood. In this study we characterized two fimbrial gene clusters present in the genome of Actinomyces naeslundii strain MG-1. By using immunoelectron microscopy and biochemical analysis, we showed that the fimQ-fimP-srtC1-fimR gene cluster encodes a fimbrial...
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