Article
Using the autism diagnostic interview--revised to increase phenotypic homogeneity in genetic studies of autism.
Biological psychiatry - 15 Feb 2007
Hus Vanessa, Pickles Andrew, Cook Edwin H, Risi Susan, Lord Catherine
Abstract excerpt
BACKGROUND: Many chromosomal regions for susceptibility to autism spectrum disorders (ASDs) have been identified, but few have reached genomewide significance. In response, researchers have attempted to increase the power of their analyses by stratifying samples to increase phenotypic homogeneity. Although homogeneity has typically been defined by a single variable, resultant groups often differ in other...
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