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Article

Dissecting the clinical heterogeneity of autism spectrum disorders through defined genotypes.

PloS one - 28 May 2010

Bruining Hilgo, de Sonneville Leo, Swaab Hanna, de Jonge Maretha, Kas Martien, van Engeland Herman, Vorstman Jacob

Abstract excerpt

BACKGROUND: The etiology of autism spectrum disorders (ASD) is largely determined by different genetic factors of variable impact. This genetic heterogeneity could be a factor to explain the clinical heterogeneity of autism spectrum disorders. Here, a first attempt is made to assess whether genetically more homogeneous ASD groups are associated with decreased phenotypic heterogeneity with respect to their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20526357
DOI: 10.1371/journal.pone.0010887
PMCID: PMC2878316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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