Article
Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes.
American journal of human genetics - 1 Mar 2003
Shao Yujun, Cuccaro M L, Hauser E R, Raiford K L, Menold M M, Wolpert C M, Ravan S A, Elston L, Decena K, Donnelly S L, Abramson R K, Wright H H, DeLong G R, Gilbert J R, Pericak-Vance M A
Abstract excerpt
Autistic disorder (AutD) is a complex genetic disease. Available evidence suggests that several genes contribute to the underlying genetic risk for the development of AutD. However, both etiologic heterogeneity and genetic heterogeneity confound the discovery of AutD-susceptibility genes. Chromosome 15q11-q13 has been identified as a strong candidate region on the basis of both the frequent occurrence of...
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