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Article

Molecular cloning and characterization of the RNA packaging-defective retrovirus SE21Q1b.

Journal of virology - 1 Jan 1992

Anderson D J, Lee P, Levine K L, Sang J S, Shah S A, Yang O O, Shank P R, Linial M L

Abstract excerpt

The nonconditional RNA packaging mutant SE21Q1b contains cis- and trans-acting defects which cause cellular mRNA, rather than viral genomic RNA, to be nonspecifically packaged into SE21Q1b viral particles. Using genomic libraries of the c-SE21Q1b quail cell line, we have been able to construct a molecular clone of the SE21Q1b provirus. Upon transfection into primary quail embryo fibroblasts, the SE21Q1b molecular...

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Identifiers

PMID: 1727484
DOI: 10.1128/JVI.66.1.204-216.1992
PMCID: PMC238277

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