Article
Diversification of function by different isoforms of conventionally shared RNA polymerase subunits.
Molecular biology of the cell - 1 Apr 2007
Devaux Sara, Kelly Steven, Lecordier Laurence, Wickstead Bill, Perez-Morga David, Pays Etienne, Vanhamme Luc, Gull Keith
Abstract excerpt
Eukaryotic nuclei contain three classes of multisubunit DNA-directed RNA polymerase. At the core of each complex is a set of 12 highly conserved subunits of which five--RPB5, RPB6, RPB8, RPB10, and RPB12--are thought to be common to all three polymerase classes. Here, we show that four distantly related eukaryotic lineages (the higher plant and three protistan) have independently expanded their repertoire of RPB5...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.