Article
A simulation test bed for hypotheses of genome evolution.
Bioinformatics (Oxford, England) - 1 Apr 2007
Beiko Robert G, Charlebois Robert L
Abstract excerpt
MOTIVATION: Microbial genomes undergo evolutionary processes such as gene family expansion and contraction, variable rates and patterns of sequence substitution and lateral genetic transfer. Simulation tools are essential for both the generation of data under different evolutionary models and the validation of analytical methods on such data. However, meaningful investigation of phenomena such as lateral genetic...
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